RNU6-354P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNU6-354P mutation is significantly associated with the RNA expression of many other genes, with 57 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-354P-associated genes across cancer lineages are AQP7P4, RNA5SP405, and CYCSP49. Each is linked with RNU6-354P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-354P-to-partner and partner-to-RNU6-354P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-354P→partner) and Y-score (partner→RNU6-354P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCAQP7P4 →+0.063+5.539<.001.00432
UCECRNA5SP405 →+0.436+4.260<.001.00732
COADCYCSP49 →+0.193+5.557<.001.00132
CESCATP5MGP7 →+0.200+5.812<.001.00332
CESCMIR153-1 →+0.795+5.418<.001.00531
CESCRNU6-1086P →+0.484+5.201<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 57 associations by consensus.

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