CYCSP49

Q-omics provides the consensus-scored CYCSP49 profile across patient tissues and cancer cell-line models. CYCSP49 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in UVM. Additionally, CYCSP49 RNA expression shows 4,082 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UVM, and TGCT as cancer lineages where CYCSP49 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes CYCSP49 survival associations across molecular data types. CYCSP49 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

CYCSP49 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	14	UVM (99)	view →

This table ranks reproducible CYCSP49 RNA expression–survival associations across cancer types. High CYCSP49 expression shows unfavorable associations in UVM, HNSC, STAD, COAD, LUSC and READ. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for CYCSP49 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.104	0.858	<.001	99	view →
HNSC	OS	Tertile	II,III,IV	0.082	0.711	<.001	72	view →
STAD	OS	Tertile	All	0.305	0.745	<.001	57	view →
COAD	OS	Tertile	III,IV	0.039	0.781	<.001	54	view →
LUSC	OS	Tertile	III,IV	0.317	0.701	.003	36	view →
READ	DFS	Tertile	III,IV	0.027	0.761	<.001	36	view →

Pink = unfavorable, green = favorable. all 14 lineages →

CYCSP49-UVM (OS)

Explore this curve interactively →