Across TCGA pan-cancer cohorts, RNU6-354P RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RNU6-354P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNU6-354P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-354P is over-expressed in tumor, although a few such as THCA and UCEC show the opposite, repressed pattern.

THCA, CHOL, and BLCA are the cancer types where RNU6-354P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-354P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.393	<.001	8	view →
CHOL	All	All	+0.385	.025	2	view →
BLCA	All	All	+0.233	.031	2	view →
UCEC	All	All	−0.190	.031	2	view →
LIHC	All	All	+0.095	.027	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RNU6-354P RNA expression & survival · all RNU6-354P data types