protein tyrosine phosphatase receptor type V, pseudogeneGenealiases: ESP · OST-PTP · PTPRV
Q-omics provides the consensus-scored PTPRVP profile across patient tissues and cancer cell-line models. PTPRVP expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, PTPRVP is differentially expressed in 13, with the highest sampling consensus in KICH. Additionally, PTPRVP RNA expression shows 16,735 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight HNSC, KICH, and UVM as cancer lineages where PTPRVP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PTPRVP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PTPRVP survival associations across molecular data types. PTPRVP RNA expression shows survival associations in the most cancer types (25), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PTPRVP RNA expression–survival associations across cancer types. High PTPRVP expression shows unfavorable associations in KIRC, UCEC and ACC, but favorable associations in HNSC, UCS and ESCA. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for PTPRVP RNA expression.
This table summarizes PTPRVP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for PTPRVP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PTPRVP shows lower tumor expression in KICH and BRCA and higher tumor expression in HNSC, KIRC, LUAD and LIHC. The KICH box plot shows higher PTPRVP RNA expression in normal versus tumor tissue (log2 FC = −0.088, t-test p < 0.001).
This table shows molecular features associated with PTPRVP in patient tissues and cancer cell lines. In patient samples, PTPRVP shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, PTPRVP RNA and mutation anchors are most strongly linked to RNA-expression features, especially in UPPER_AERODIGESTIVE_TRACT, while CRISPR and shRNA rows add functional-dependency signals in OESOPHAGUS.
