PTPRVP

Across TCGA pan-cancer cohorts, PTPRVP RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated PTPRVP data layer compared with 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PTPRVP RNA is associated with better overall survival. In most high-consensus cancer types, elevated PTPRVP expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, KIRC, and UCS are the cancer types where PTPRVP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.725	0.599	<.001	107	view →
KIRC	DFS	Median	All	0.516	0.696	<.001	86	view →
UCS	DFS	Quartile	II,III,IV	0.765	0.172	<.001	72	view →
UCEC	DFS	Quartile	III,IV	0.655	0.880	.001	58	view →
ACC	DFS	Quartile	All	0.226	0.722	<.001	51	view →
READ	OS	Median	All	0.781	0.519	<.001	40	view →
ESCA	OS	Tertile	III,IV	0.603	0.302	.005	40	view →
LUAD	OS	Median	All	0.758	0.625	<.001	38	view →
COAD	DFS	Median	II,III,IV	0.341	0.585	.005	25	view →
LGG	DFS	Median	All	0.325	0.454	<.001	22	view →
CESC	OS	Median	IV	0.774	0.388	.023	18	view →
OV	OS	Quartile	IV	0.482	0.901	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

PTPRVP–HNSC (OS)

Open the HNSC breakdown →