Q-omics provides the consensus-scored PALM2AKAP2 profile across patient tissues and cancer cell-line models. PALM2AKAP2 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, PALM2AKAP2 is differentially expressed in 13, with the highest sampling consensus in HNSC. Additionally, PALM2AKAP2 protein abundance shows 28,195 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight KIRC, HNSC, and LSCC as cancer lineages where PALM2AKAP2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PALM2AKAP2 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PALM2AKAP2 survival associations across molecular data types. PALM2AKAP2 RNA expression shows survival associations in the most cancer types (24), followed by mutation status (3) and mass-spec protein abundance (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PALM2AKAP2 RNA expression–survival associations across cancer types. High PALM2AKAP2 expression shows unfavorable associations in BLCA, LUSC, THCA and STAD, but favorable associations in KIRC and SCLC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for PALM2AKAP2 RNA expression.
This table summarizes PALM2AKAP2 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13, while mass-spec protein shows differences in 6. The strongest signals are observed in HNSC for RNA and LUAD for protein.
This table ranks reproducible tumor–normal expression differences for PALM2AKAP2. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PALM2AKAP2 shows lower tumor expression in THCA, BRCA and KICH and higher tumor expression in HNSC, COAD and STAD. The HNSC box plot shows higher PALM2AKAP2 RNA expression in tumor versus normal tissue (log2 FC = +0.196, t-test p < 0.001).
This table shows molecular features associated with PALM2AKAP2 in patient tissues and cancer cell lines. In patient samples, PALM2AKAP2 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set. In cancer cell lines, PALM2AKAP2 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LARGE_INTESTINE, while CRISPR and shRNA rows add functional-dependency signals in UPPER_AERODIGESTIVE_TRACT and BREAST.
