PALM2AKAP2

Across TCGA patient cohorts, PALM2AKAP2 mutation is significantly associated with the RNA expression of many other genes, with 7,923 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PALM2AKAP2-associated genes across cancer lineages are ITGB1BP1, HMG20B, and LINC01399. Each is linked with PALM2AKAP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both PALM2AKAP2-to-partner and partner-to-PALM2AKAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGB1BP1 grouped by PALM2AKAP2-low versus PALM2AKAP2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PALM2AKAP2→partner) and Y-score (partner→PALM2AKAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ITGB1BP1 →	+0.499	+3.119	<.001	<.001	3	4
SKCM	HMG20B →	+0.527	+3.334	.006	.005	3	4
UCEC	LINC01399 →	+0.120	+1.284	<.001	<.001	3	4
UCEC	NDUFA8 →	+0.312	+3.000	<.001	<.001	3	4
UCEC	COX5A →	+0.321	+1.436	<.001	<.001	3	3
UCEC	TMEM107 →	+0.366	+1.315	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,923 associations by consensus.

ITGB1BP1 by PALM2AKAP2 expression — SKCM

Explore this box plot interactively →