PALM2AKAP2

Across TCGA cell cohorts, PALM2AKAP2 mutation is significantly associated with the RNA expression of many other genes, with 478 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PALM2AKAP2-associated genes across cancer lineages are CFHR2, CSN1S1, and IL4. Each is linked with PALM2AKAP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PALM2AKAP2-to-partner and partner-to-PALM2AKAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by PALM2AKAP2-low versus PALM2AKAP2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PALM2AKAP2→partner) and Y-score (partner→PALM2AKAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CFHR2 →	+0.174	+4.124	<.001	<.001	3	3
LUNG_NSCLC_LUAD	CSN1S1 →	+0.041	+4.887	<.001	.009	3	2
BLOOD_Leukemia	IL4 →	+1.758	+3.007	<.001	.007	3	2
BLOOD_Leukemia	OR4D1 →	+0.140	+3.118	<.001	.005	3	2
BLOOD_Leukemia	WFDC12 →	+0.145	+3.704	<.001	.001	3	2
PANCREAS	C4orf50 →	+0.056	+4.011	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 478 associations by consensus.

CFHR2 by PALM2AKAP2 expression — BLOOD_Leukemia

Explore this box plot interactively →