OR52N5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR52N5 mutation is significantly associated with the RNA expression of many other genes, with 2,763 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52N5-associated genes across cancer lineages are TRMT61A, FDX2, and RNA5SP62. Each is linked with OR52N5 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52N5-to-partner and partner-to-OR52N5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRMT61A grouped by OR52N5-low versus OR52N5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N5→partner) and Y-score (partner→OR52N5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTRMT61A →+0.392+2.415.006.00333
SKCMFDX2 →+0.368+3.334.002.00533
COADRNA5SP62 →+0.834+4.537.003.00632
COADRNY3P13 →+1.116+3.993<.001.00532
COADRNA5SP53 →+0.774+4.221<.001.00332
COADMIR548E →+0.752+4.308<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,763 associations by consensus.

TRMT61A by OR52N5 expression — UCEC

Box plot of TRMT61A in OR52N5-low vs OR52N5-high samples in UCEC.

Explore this box plot interactively →

Exploration