olfactory receptor family 3 subfamily A member 1Genealiases: OLFRA03 · OR17-40 · OR17-82 · OR40
Q-omics provides the consensus-scored OR3A1 profile across patient tissues and cancer cell-line models. OR3A1 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in LIHC. Among the 18 cancer types available for tumor–normal comparison, OR3A1 is differentially expressed in 4, with the highest sampling consensus in KICH. Additionally, OR3A1 RNA expression shows 10,482 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight LIHC, KICH, and THYM as cancer lineages where OR3A1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR3A1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR3A1 survival associations across molecular data types. OR3A1 RNA expression shows survival associations in the most cancer types (15), followed by mutation status (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR3A1 RNA expression–survival associations across cancer types. High OR3A1 expression shows unfavorable associations in LIHC, BLCA, LUSC, ACC and COAD, but favorable associations in SKCM. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for OR3A1 RNA expression.
This table summarizes OR3A1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for OR3A1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OR3A1 shows lower tumor expression in KICH, PRAD, COAD and LUAD. The KICH box plot shows higher OR3A1 RNA expression in normal versus tumor tissue (log2 FC = −0.127, t-test p = .001).
This table shows molecular features associated with OR3A1 in patient tissues and cancer cell lines. In patient samples, OR3A1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, OR3A1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in CNS, while CRISPR and shRNA rows add functional-dependency signals in OVARY and LARGE_INTESTINE.
