OR3A1

Across TCGA pan-cancer cohorts, OR3A1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of OR3A1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where OR3A1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR3A1 is over-expressed in tumor, although a few such as KICH and PRAD show the opposite, repressed pattern.

KICH, PRAD, and COAD are the cancer types where OR3A1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR3A1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.127	.001	4	view →
PRAD	All	All	−0.045	.043	2	view →
COAD	Male	All	−0.044	.001	2	view →
LUAD	Male	II,III,IV	−0.062	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

OR3A1–KICH

Open the KICH breakdown →