OR3A1

Across TCGA cell cohorts, OR3A1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR3A1-associated genes across cancer lineages are BPY2, BPY2B, and BPY2C. Each is linked with OR3A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR3A1-to-partner and partner-to-OR3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPY2 grouped by OR3A1-low versus OR3A1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR3A1→partner) and Y-score (partner→OR3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	BPY2 →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	BPY2B →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	BPY2C →	+0.006	+5.228	<.001	.005	3	1
LARGE_INTESTINE	DAZ4 →	+0.123	+3.240	.004	.004	3	1
LARGE_INTESTINE	DAZ2 →	+0.127	+3.678	.004	.001	3	1
LARGE_INTESTINE	EVPLL →	+0.525	+3.304	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

BPY2 by OR3A1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →