OR3A1

Across TCGA patient cohorts, OR3A1 mutation is significantly associated with the RNA expression of many other genes, with 609 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR3A1-associated genes across cancer lineages are MFSD4A, RNVU1-28, and OR2M4. Each is linked with OR3A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR3A1-to-partner and partner-to-OR3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MFSD4A grouped by OR3A1-low versus OR3A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR3A1→partner) and Y-score (partner→OR3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MFSD4A →	-0.821	-3.437	.008	.005	3	2
UCEC	RNVU1-28 →	+1.033	+2.635	<.001	.002	3	2
HNSC	OR2M4 →	+0.061	+5.069	<.001	.008	3	2
HNSC	RNU6-220P →	+0.395	+5.736	<.001	.003	3	2
BLCA	NPVF →	+0.098	+5.444	<.001	.002	3	2
COAD	SNRPGP8 →	+0.303	+5.136	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 609 associations by consensus.

MFSD4A by OR3A1 expression — UCEC

Explore this box plot interactively →