OR3A1

Across TCGA patient cohorts, OR3A1 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR3A1-associated genes across cancer lineages are p21, P-Cadherin, and Di-Ras3. Each is linked with OR3A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR3A1-to-partner and partner-to-OR3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p21 grouped by OR3A1-low versus OR3A1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR3A1→partner) and Y-score (partner→OR3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	p21 →	-0.466	-3.000	.038	.035	3	1
UCEC	P-Cadherin →	-0.226	-2.986	.006	.037	3	1
UCEC	Di-Ras3 →	-0.273	-3.000	.001	.037	2	1
SKCM	A-Raf_pS299 →	+0.151	+3.321	.042	.010	1	1
UCEC	14-3-3_beta →	-0.173	-2.986	.002	.037	1	1
UCEC	Caspase-8 →	-0.356	-3.000	.014	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

p21 by OR3A1 expression — SKCM

Explore this box plot interactively →