Q-omics provides the consensus-scored OR2Y1 profile across patient tissues and cancer cell-line models. OR2Y1 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in DLBC. Among the 18 cancer types available for tumor–normal comparison, OR2Y1 is differentially expressed in 1, with the highest sampling consensus in THCA. Additionally, OR2Y1 RNA expression shows 6,171 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight DLBC, THCA, and STAD as cancer lineages where OR2Y1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OR2Y1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OR2Y1 survival associations across molecular data types. OR2Y1 RNA expression shows survival associations in the most cancer types (8), followed by mutation status (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OR2Y1 RNA expression–survival associations across cancer types. High OR2Y1 expression shows unfavorable associations in DLBC, SCLC, BLCA, LIHC and KIRC, but favorable associations in ESCA. The DLBC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify DLBC as the clearest survival context for OR2Y1 RNA expression.
This table summarizes OR2Y1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for OR2Y1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OR2Y1 shows higher tumor expression in THCA. The THCA box plot shows higher OR2Y1 RNA expression in tumor versus normal tissue (log2 FC = +0.006, t-test p = .015).
This table shows molecular features associated with OR2Y1 in patient tissues and cancer cell lines. In patient samples, OR2Y1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set. In cancer cell lines, OR2Y1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Leukemia, while CRISPR and shRNA rows add functional-dependency signals in BREAST and BONE.
