OR2Y1

Across TCGA cell cohorts, OR2Y1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible OR2Y1-associated genes across cancer lineages are ARGFX, AVPR1B, and DMRTB1. Each is linked with OR2Y1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2Y1-to-partner and partner-to-OR2Y1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARGFX grouped by OR2Y1-low versus OR2Y1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2Y1→partner) and Y-score (partner→OR2Y1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ARGFX →	+0.020	+6.022	<.001	.001	3	1
SKIN	AVPR1B →	+0.013	+5.415	<.001	.004	3	1
LUNG_NSCLC_LUAD	DMRTB1 →	+0.006	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	ADIPOQ →	+0.029	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRTAP7-1 →	+0.147	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

ARGFX by OR2Y1 expression — LARGE_INTESTINE

Explore this box plot interactively →