Q-omics provides the consensus-scored AVPR1B profile across patient tissues and cancer cell-line models. AVPR1B expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, AVPR1B is differentially expressed in 10, with the highest sampling consensus in KIRC. Additionally, AVPR1B RNA expression shows 16,002 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRC, and TGCT as cancer lineages where AVPR1B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for AVPR1B — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes AVPR1B survival associations across molecular data types. AVPR1B RNA expression shows survival associations in the most cancer types (21), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible AVPR1B RNA expression–survival associations across cancer types. High AVPR1B expression shows favorable associations in KIRC, SCLC, ESCA, LAML, PAAD and CHOL. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for AVPR1B RNA expression.
This table summarizes AVPR1B tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for AVPR1B. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. AVPR1B shows lower tumor expression in KICH and COAD and higher tumor expression in KIRC, UCEC, KIRP and LUAD. The KIRC box plot shows higher AVPR1B RNA expression in tumor versus normal tissue (log2 FC = +1.958, t-test p < 0.001).
This table shows molecular features associated with AVPR1B in patient tissues and cancer cell lines. In patient samples, AVPR1B shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set. In cancer cell lines, AVPR1B RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BONE, while CRISPR and shRNA rows add functional-dependency signals in OVARY and LARGE_INTESTINE.
