Across TCGA cell cohorts, AVPR1B mutation is significantly associated with the RNA expression of many other genes, with 216 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AVPR1B-associated genes across cancer lineages are OR51A4, SMIM28, and MTRNR2L6. Each is linked with AVPR1B in more than 1 cancer types. Because this analysis shows association rather than direction, both AVPR1B-to-partner and partner-to-AVPR1B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AVPR1B→partner) and Y-score (partner→AVPR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR51A4 →	+0.006	+4.022	<.001	.006	3	1
SKIN	SMIM28 →	+0.013	+4.022	<.001	.006	3	1
SKIN	MTRNR2L6 →	+0.032	+3.632	<.001	.003	3	1
LARGE_INTESTINE	GCAT →	+1.182	+3.321	.002	.003	3	1
LARGE_INTESTINE	CBY1 →	+0.656	+2.459	<.001	.005	3	1
LARGE_INTESTINE	TXN2 →	+0.458	+3.588	.009	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 216 associations by consensus.

Exploration

AVPR1B survival (RNA) · tumor vs normal (RNA) · all AVPR1B data types