OR2Y1

Across TCGA patient cohorts, OR2Y1 mutation is significantly associated with the RNA expression of many other genes, with 1,439 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2Y1-associated genes across cancer lineages are MIR4779, MIR6792, and TXNP3. Each is linked with OR2Y1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR2Y1-to-partner and partner-to-OR2Y1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4779 grouped by OR2Y1-low versus OR2Y1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2Y1→partner) and Y-score (partner→OR2Y1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4779 →	+0.133	+2.648	<.001	.004	3	3
BRCA	MIR6792 →	+0.433	+4.971	<.001	.005	3	2
SKCM	TXNP3 →	+0.043	+2.436	<.001	.003	3	2
SKCM	CSTF3-DT →	+0.093	+1.757	.008	.005	3	2
UCEC	CRYBB2P1 →	+0.578	+3.385	.001	.004	3	2
UCEC	POLD2 →	+0.479	+3.609	.009	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,439 associations by consensus.

MIR4779 by OR2Y1 expression — SKCM

Explore this box plot interactively →