OPCML-IT2

Across TCGA patient cohorts, OPCML-IT2 RNA expression is significantly associated with the RNA expression of many other genes, with 7,330 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible OPCML-IT2-associated genes across cancer lineages are RNMTL1P2, RPL17P19, and RN7SKP263. Each is linked with OPCML-IT2 in more than 12 cancer types. Because this analysis shows association rather than direction, both OPCML-IT2-to-partner and partner-to-OPCML-IT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OPCML-IT2 versus RNMTL1P2 in LUSC, with a Pearson correlation of 0.83.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OPCML-IT2→partner) and Y-score (partner→OPCML-IT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNMTL1P2 →	+0.511	+0.113	<.001	<.001	3	13
LUAD	RPL17P19 →	+0.682	+0.186	<.001	<.001	3	13
LUSC	RN7SKP263 →	+0.512	+0.093	<.001	<.001	3	12
LUSC	RNU6ATAC6P →	+0.640	+0.113	<.001	<.001	3	11
LUSC	OR13Z1P →	+0.571	+0.058	<.001	<.001	3	11
BRCA	IGSF21-AS1 →	+0.850	+0.050	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,330 associations by consensus.

OPCML-IT2 vs RNMTL1P2 — LUSC

Explore this scatter interactively →