Q-omics provides the consensus-scored MSMP profile across patient tissues and cancer cell-line models. MSMP expression is associated with patient survival in 1 of 34 cancer types, with the highest sampling consensus in SCLC. Additionally, MSMP RNA expression shows 4,521 significant gene co-expression associations, with the highest sampling consensus in SCLC. Together, these results highlight SCLC as cancer lineages where MSMP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for MSMP — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes MSMP survival associations across molecular data types. MSMP RNA expression shows survival associations in the most cancer types (1), followed by mutation status (2) and mass-spec protein abundance (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MSMP data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
Mutation	Kaplan–Meier	2	SKCM (6)	view →
Protein (mass-spec)	Kaplan–Meier	1	GBM (4)	view →
RNA	Kaplan–Meier	1	SCLC (48)	view →

This table ranks reproducible MSMP RNA expression–survival associations across cancer types. High MSMP expression shows favorable associations in SCLC. The SCLC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .004). Together, the overview and detailed table identify SCLC as the clearest survival context for MSMP RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Tertile	All	0.654	0.358	.004	48	view →

Pink = unfavorable, green = favorable. all 1 lineages →

MSMP-SCLC (OS)

Kaplan–Meier survival curve for MSMP RNA expression in SCLC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MSMP in patient tissues and cancer cell lines. In patient samples, MSMP shows the broadest associations at the RNA and protein expression levels, with SCLC recurring as the lineage with the largest associated feature set. In cancer cell lines, MSMP RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LIVER, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Leukemia.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	4,521	SCLC (4521)	view →
Function (RNA)	988	SCLC (988)	view →
▼Mutation
RNA	152	UCEC (150)	view →
▼Protein (mass-spec)
RNA	38	GBM (38)	view →
Protein (mass-spec)	24	GBM (24)	view →

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼CRISPR
CRISPR	1,873	LIVER (192)	view →
RNA	1,216	LIVER (238)	view →
▼RNA
RNA	5,403	BLOOD_Leukemia (1981)	view →
Function (RNA)	2,419	BLOOD_Leukemia (1139)	view →