Across TCGA patient cohorts, MSMP mutation is significantly associated with the RNA expression of many other genes, with 152 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MSMP-associated genes across cancer lineages are RNU6-812P, USP37P1, and OR10AE1P. Each is linked with MSMP in more than 1 cancer types. Because this analysis shows association rather than direction, both MSMP-to-partner and partner-to-MSMP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSMP→partner) and Y-score (partner→MSMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-812P →	+0.390	+7.924	<.001	.008	3	2
UCEC	USP37P1 →	+0.117	+5.470	<.001	.001	3	1
UCEC	OR10AE1P →	+0.208	+3.935	<.001	.003	3	1
UCEC	MIR8054 →	+0.690	+4.877	<.001	.003	3	1
UCEC	MIR6509 →	+0.703	+3.277	.002	.009	3	1
UCEC	RN7SL495P →	+0.263	+4.335	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 152 associations by consensus.

Exploration

MSMP survival (RNA) · tumor vs normal (RNA) · all MSMP data types