Across TCGA patient cohorts, MSMP protein abundance is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MSMP-associated genes across cancer lineages are PFKFB2, STK33, and SLC34A1. Each is linked with MSMP in more than 1 cancer types. Because this analysis shows association rather than direction, both MSMP-to-partner and partner-to-MSMP results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MSMP→partner) and Y-score (partner→MSMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PFKFB2 →	-1.310	-1.668	.002	.008	3	1
GBM	STK33 →	-1.196	-1.924	<.001	.003	3	1
GBM	SLC34A1 →	+0.065	+3.993	.002	.006	3	1
GBM	PLAAT2 →	-0.416	-2.566	.003	.008	3	1
GBM	XPC →	-0.443	-1.744	.005	.005	3	1
GBM	HS3ST6 →	+0.083	+2.697	.009	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

MSMP survival (RNA) · tumor vs normal (RNA) · all MSMP data types