maestro heat like repeat family member 3, pseudogeneGenealiases: []
Q-omics provides the consensus-scored MROH3P profile across patient tissues and cancer cell-line models. MROH3P expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, MROH3P is differentially expressed in 11, with the highest sampling consensus in COAD. Additionally, MROH3P RNA expression shows 9,676 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight LUAD, COAD, and ESCA as cancer lineages where MROH3P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MROH3P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MROH3P survival associations across molecular data types. MROH3P RNA expression shows survival associations in the most cancer types (18), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MROH3P RNA expression–survival associations across cancer types. High MROH3P expression shows unfavorable associations in LUAD, KICH, UCEC, LIHC and READ, but favorable associations in COAD. The LUAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUAD as the clearest survival context for MROH3P RNA expression.
This table summarizes MROH3P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for MROH3P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MROH3P shows lower tumor expression in COAD and KICH and higher tumor expression in LUAD, LUSC, KIRC and STAD. The COAD box plot shows higher MROH3P RNA expression in normal versus tumor tissue (log2 FC = −0.538, t-test p < 0.001).
This table shows molecular features associated with MROH3P in patient tissues and cancer cell lines. In patient samples, MROH3P shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.
