MROH3P

Across TCGA pan-cancer cohorts, MROH3P RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of MROH3P’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where MROH3P RNA is repressed in tumor relative to normal tissue. In most cancer types MROH3P is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, LUAD, and LUSC are the cancer types where MROH3P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MROH3P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.538	<.001	8	view →
LUAD	All	All	+0.410	<.001	7	view →
LUSC	All	All	+0.380	<.001	7	view →
KIRC	Male	II,III,IV	+0.106	.001	7	view →
STAD	All	All	+0.569	.009	5	view →
KICH	All	All	−0.061	<.001	5	view →
BRCA	Female	All	+0.108	.014	4	view →
LIHC	All	All	+0.082	.004	3	view →
ESCA	All	II,III,IV	+1.925	.047	2	view →
CHOL	All	All	+0.767	.009	2	view →
UCEC	All	All	+0.125	.013	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

MROH3P–COAD

Open the COAD breakdown →