MROH3P

Across TCGA pan-cancer cohorts, MROH3P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated MROH3P data layer compared with 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MROH3P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MROH3P expression acts as an unfavorable survival marker, although some lineages such as COAD and BLCA show a favorable association.

LUAD, KICH, and UCEC are the cancer types where MROH3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.224	0.514	<.001	107	view →
KICH	OS	Tertile	II,III,IV	0.708	0.984	<.001	93	view →
UCEC	OS	Median	All	0.482	0.845	<.001	86	view →
LIHC	OS	Tertile	III,IV	0.294	0.687	.002	51	view →
COAD	DFS	Quartile	IV	0.620	0.179	.002	30	view →
READ	DFS	Median	III,IV	0.312	0.774	.004	29	view →
OV	DFS	Median	IV	0.336	0.574	.007	28	view →
LGG	OS	Median	All	0.743	0.865	<.001	27	view →
BLCA	OS	Quartile	All	0.797	0.640	.002	26	view →
DLBC	OS	Quartile	II,III,IV	0.679	1.000	.033	23	view →
MESO	DFS	Quartile	IV	0.132	0.378	.016	8	view →
SKCM	OS	Median	II,III,IV	0.767	0.876	.013	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

MROH3P–LUAD (DFS)

Open the LUAD breakdown →