Q-omics provides the consensus-scored MMP1 profile across patient tissues and cancer cell-line models. MMP1 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, MMP1 is differentially expressed in 17, with the highest sampling consensus in HNSC. Additionally, MMP1 RNA expression shows 16,835 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight KIRP, HNSC, and GBM as cancer lineages where MMP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MMP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MMP1 survival associations across molecular data types. MMP1 RNA expression shows survival associations in the most cancer types (25), followed by mass-spec protein abundance (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MMP1 RNA expression–survival associations across cancer types. High MMP1 expression shows unfavorable associations in KIRP, UVM, KICH, LIHC, ACC and THCA. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for MMP1 RNA expression.
This table summarizes MMP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 17, while mass-spec protein shows differences in 5. The strongest signals are observed in HNSC for RNA and HNSC for protein.
This table ranks reproducible tumor–normal expression differences for MMP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MMP1 shows higher tumor expression in HNSC, COAD, THCA, LUSC, LUAD and READ. The HNSC box plot shows higher MMP1 RNA expression in tumor versus normal tissue (log2 FC = +7.210, t-test p < 0.001).
This table shows molecular features associated with MMP1 in patient tissues and cancer cell lines. In patient samples, MMP1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set. In cancer cell lines, MMP1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_SCLC, while CRISPR and shRNA rows add functional-dependency signals in OESOPHAGUS and BLOOD_Lymphoma.
