Across TCGA patient cohorts, MMP1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,349 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MMP1-associated genes across cancer lineages are ITGA5, DSE, and MFAP2. Each is linked with MMP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MMP1-to-partner and partner-to-MMP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP1→partner) and Y-score (partner→MMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ITGA5 →	+1.500	+1.205	<.001	<.001	3	6
GBM	DSE →	+0.677	+1.105	.008	.008	2	6
BRCA	MFAP2 →	+1.343	+0.882	<.001	<.001	3	5
COAD	INHBA →	+1.442	+0.961	<.001	.001	3	5
LSCC	MMP13 →	+2.270	+1.061	<.001	<.001	3	5
COAD	FN1 →	+2.635	+1.143	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,349 associations by consensus.

Exploration

MMP1 survival (RNA) · tumor vs normal (RNA) · all MMP1 data types