Across TCGA patient cohorts, MMP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,835 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MMP1-associated proteins across cancer lineages are PLAU, PPP1R18_S368, and FAP. Each is linked with MMP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both MMP1-to-partner and partner-to-MMP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MMP1→partner) and Y-score (partner→MMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PLAU →	+0.931	+2.382	.001	<.001	3	8
OV	PPP1R18_S368 →	+0.766	+1.534	.001	<.001	3	8
OV	FAP →	+1.094	+1.553	<.001	<.001	3	7
OV	FN1 →	+1.028	+1.407	<.001	.001	3	7
BRCA	PRTN3 →	+1.366	+2.330	<.001	<.001	3	6
GBM	PLOD1 →	+0.645	+1.021	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,835 associations by consensus.

Exploration

MMP1 survival (RNA) · tumor vs normal (RNA) · all MMP1 data types