Across TCGA patient cohorts, MIRLET7C mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MIRLET7C-associated genes across cancer lineages are IL9, MIR5692C1, and SFXN4P1. Each is linked with MIRLET7C in more than 1 cancer types. Because this analysis shows association rather than direction, both MIRLET7C-to-partner and partner-to-MIRLET7C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIRLET7C→partner) and Y-score (partner→MIRLET7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	IL9 →	+0.468	+5.037	<.001	.009	3	1
SKCM	MIR5692C1 →	+0.767	+6.328	<.001	.001	3	1
SKCM	SFXN4P1 →	+0.099	+5.159	<.001	.007	3	1
SKCM	RNU6-490P →	+0.383	+5.037	<.001	.009	3	1
SKCM	RNU2-36P →	+0.239	+5.362	<.001	.005	3	1
SKCM	STSP1 →	+0.043	+5.680	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

MIRLET7C survival (RNA) · tumor vs normal (RNA) · all MIRLET7C data types