MIR4280HG

Across TCGA patient cohorts, MIR4280HG mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MIR4280HG-associated genes across cancer lineages are MIR4470, MIR4692, and RNY1P16. Each is linked with MIR4280HG in more than 1 cancer types. Because this analysis shows association rather than direction, both MIR4280HG-to-partner and partner-to-MIR4280HG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4470 grouped by MIR4280HG-low versus MIR4280HG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MIR4280HG→partner) and Y-score (partner→MIR4280HG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4470 →	+0.957	+4.771	<.001	.001	3	1
UCEC	MIR4692 →	+0.568	+4.868	<.001	.004	3	1
UCEC	RNY1P16 →	+1.236	+3.976	<.001	.006	3	1
UCEC	RNU6-238P →	+0.860	+5.134	<.001	<.001	3	1
UCEC	RNU2-5P →	+0.766	+3.831	<.001	.009	3	1
UCEC	RN7SKP144 →	+0.148	+5.660	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MIR4470 by MIR4280HG expression — UCEC

Explore this box plot interactively →