MIR4280HG

Across TCGA pan-cancer cohorts, MIR4280HG RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MIR4280HG data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MIR4280HG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated MIR4280HG expression acts as an unfavorable survival marker, although some lineages such as LUAD and MESO show a favorable association.

KIRC, ACC, and THYM are the cancer types where MIR4280HG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	III,IV	0.304	0.544	.001	114	view →
ACC	DFS	Tertile	IV	0.010	0.383	<.001	27	view →
THYM	OS	Tertile	III,IV	0.212	1.000	.014	18	view →
LUAD	DFS	Tertile	II,III,IV	0.708	0.356	.018	18	view →
MESO	OS	Tertile	II,III,IV	0.829	0.532	.022	15	view →
LIHC	DFS	Tertile	All	0.419	0.571	.040	15	view →
DLBC	OS	Median	III,IV	0.344	1.000	.024	7	view →
ESCA	OS	Quartile	II,III,IV	0.105	0.902	.001	6	view →
SKCM	DFS	Tertile	IV	0.031	0.727	.045	6	view →
KICH	OS	Quartile	III,IV	0.178	0.816	.001	5	view →
THCA	OS	Median	All	1.000	0.865	.041	2	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MIR4280HG–KIRC (DFS)

Open the KIRC breakdown →