MIR4280HG

Across TCGA pan-cancer cohorts, MIR4280HG RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of MIR4280HG’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MIR4280HG RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MIR4280HG is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

KIRC, LUAD, and THCA are the cancer types where MIR4280HG tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MIR4280HG RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.005	.002	5	view →
LUAD	All	All	+0.015	<.001	4	view →
THCA	All	All	+0.040	<.001	3	view →
COAD	Female	II,III,IV	−0.010	.014	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

MIR4280HG–KIRC

Open the KIRC breakdown →