Q-omics provides the consensus-scored LYRM9 profile across patient tissues and cancer cell-line models. LYRM9 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, LYRM9 is differentially expressed in 14, with the highest sampling consensus in KICH. Additionally, LYRM9 RNA expression shows 18,056 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight MESO, KICH, and UVM as cancer lineages where LYRM9 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LYRM9 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LYRM9 survival associations across molecular data types. LYRM9 RNA expression shows survival associations in the most cancer types (25), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LYRM9 RNA expression–survival associations across cancer types. High LYRM9 expression shows unfavorable associations in LAML, but favorable associations in MESO, KIRP, LUAD, ACC and KIRC. The MESO Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for LYRM9 RNA expression.
This table summarizes LYRM9 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for LYRM9. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LYRM9 shows lower tumor expression in KICH, KIRC, THCA, LUAD, LUSC and UCEC. The KICH box plot shows higher LYRM9 RNA expression in normal versus tumor tissue (log2 FC = −2.524, t-test p < 0.001).
This table shows molecular features associated with LYRM9 in patient tissues and cancer cell lines. In patient samples, LYRM9 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, LYRM9 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in CNS, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Lymphoma.
