LRRD1

Across TCGA cell cohorts, LRRD1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LRRD1-associated genes across cancer lineages are C14orf180, CT45A6, and TAAR8. Each is linked with LRRD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRRD1-to-partner and partner-to-LRRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C14orf180 grouped by LRRD1-low versus LRRD1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRRD1→partner) and Y-score (partner→LRRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	C14orf180 →	+0.389	+5.087	<.001	.004	3	1
URINARY_TRACT	CT45A6 →	+0.036	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUAD	TAAR8 →	+0.022	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	RNASE11 →	+0.215	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR52N5 →	+0.071	+5.228	.006	.005	3	1
LUNG_NSCLC_LUAD	OR56B1 →	+0.034	+4.887	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

C14orf180 by LRRD1 expression — URINARY_TRACT

Explore this box plot interactively →