LRRD1

Across TCGA pan-cancer cohorts, LRRD1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated LRRD1 data layer compared with 4 for mutation status.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher LRRD1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LRRD1 expression acts as an unfavorable survival marker, although some lineages such as UCS and SCLC show a favorable association.

UCS, KIRC, and DLBC are the cancer types where LRRD1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	II,III,IV	0.652	0.246	<.001	66	view →
KIRC	DFS	Tertile	All	0.519	0.693	.002	65	view →
DLBC	OS	Median	All	0.726	1.000	.002	53	view →
UVM	DFS	Quartile	III,IV	0.197	0.700	<.001	46	view →
LUSC	DFS	Tertile	III,IV	0.478	0.802	<.001	37	view →
READ	OS	Quartile	II,III,IV	0.593	0.933	.003	37	view →
SCLC	DFS	Median	All	1.000	0.568	.001	28	view →
LGG	DFS	Tertile	All	0.679	0.832	<.001	25	view →
PAAD	DFS	Quartile	All	0.517	0.211	.004	24	view →
BLCA	OS	Median	II,III,IV	0.760	0.663	.008	22	view →
LUAD	OS	Quartile	II,III,IV	0.799	0.498	.001	22	view →
PRAD	DFS	Tertile	All	0.840	0.925	.007	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

LRRD1–UCS (DFS)

Open the UCS breakdown →