long intergenic non-protein coding RNA 303Genealiases: C1orf157 · NCRNA00303
Q-omics provides the consensus-scored LINC00303 profile across patient tissues and cancer cell-line models. LINC00303 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, LINC00303 is differentially expressed in 10, with the highest sampling consensus in READ. Additionally, LINC00303 RNA expression shows 7,514 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UCS, READ, and TGCT as cancer lineages where LINC00303 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00303 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00303 survival associations across molecular data types. LINC00303 RNA expression shows survival associations in the most cancer types (18), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00303 RNA expression–survival associations across cancer types. High LINC00303 expression shows unfavorable associations in UCS, KICH, COAD and BLCA, but favorable associations in PAAD and LUAD. The UCS Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCS as the clearest survival context for LINC00303 RNA expression.
This table summarizes LINC00303 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in READ for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00303. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00303 shows lower tumor expression in READ, PAAD and THCA and higher tumor expression in UCEC, LIHC and KIRC. The READ box plot shows higher LINC00303 RNA expression in normal versus tumor tissue (log2 FC = −0.040, t-test p = .002).
This table shows molecular features associated with LINC00303 in patient tissues and cancer cell lines. In patient samples, LINC00303 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set. In cancer cell lines, LINC00303 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in SKIN, while CRISPR and shRNA rows add functional-dependency signals in LUNG_SCLC.
