LINC00303

Across TCGA patient cohorts, LINC00303 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00303-associated genes across cancer lineages are A-Raf_pS299, ERK2, and GATA6. Each is linked with LINC00303 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00303-to-partner and partner-to-LINC00303 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by LINC00303-low versus LINC00303-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00303→partner) and Y-score (partner→LINC00303) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.202	-3.321	<.001	.010	3	1
UCEC	ERK2 →	+0.294	+3.459	.002	.005	3	1
UCEC	GATA6 →	-0.189	-2.314	.014	.035	3	1
UCEC	INPP4B →	-0.372	-3.000	.022	.036	3	1
UCEC	JNK_pT183_Y185 →	-0.196	-2.308	.020	.036	3	1
UCEC	MEK1 →	+0.614	+3.459	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

A-Raf_pS299 by LINC00303 expression — UCEC

Explore this box plot interactively →