LINC00303

Across TCGA pan-cancer cohorts, LINC00303 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated LINC00303 data layer compared with 3 for mutation status.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher LINC00303 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00303 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUAD show a favorable association.

UCS, KICH, and COAD are the cancer types where LINC00303 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	III,IV	0.199	0.566	<.001	80	view →
KICH	DFS	Quartile	II,III,IV	0.283	0.935	<.001	67	view →
COAD	DFS	Tertile	IV	0.254	0.566	<.001	59	view →
BLCA	OS	Median	IV	0.312	0.731	<.001	42	view →
PAAD	OS	Median	All	0.656	0.396	.010	39	view →
LUAD	DFS	Tertile	All	0.504	0.284	.005	27	view →
OV	OS	Quartile	III,IV	0.740	0.619	.016	20	view →
LGG	DFS	Quartile	All	0.766	0.934	.002	18	view →
BRCA	DFS	Tertile	III,IV	0.813	0.898	.018	16	view →
CHOL	OS	Tertile	All	0.164	0.831	.001	15	view →
UCEC	DFS	Median	IV	0.872	0.517	.002	14	view →
SARC	DFS	Tertile	All	0.516	0.288	.004	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

LINC00303–UCS (DFS)

Open the UCS breakdown →