Across TCGA pan-cancer cohorts, LINC00303 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LINC00303’s most consistent transcriptional readouts.
The strongest signal is observed in rectum adenocarcinoma (READ), where LINC00303 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC00303 is over-expressed in tumor, although a few such as READ and PAAD show the opposite, repressed pattern.
READ, UCEC, and PAAD are the cancer types where LINC00303 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC00303 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.