Across TCGA patient cohorts, KRTAP5-11 mutation is significantly associated with the RNA expression of many other genes, with 222 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP5-11-associated genes across cancer lineages are MTDHP1, CASTOR2, and RN7SL495P. Each is linked with KRTAP5-11 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP5-11-to-partner and partner-to-KRTAP5-11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP5-11→partner) and Y-score (partner→KRTAP5-11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MTDHP1 →	-0.288	-2.831	.005	.002	3	1
UCEC	CASTOR2 →	+0.812	+2.939	.001	<.001	3	1
UCEC	RN7SL495P →	+0.100	+3.113	<.001	.006	3	1
BRCA	DUXAP11 →	+0.079	+7.731	<.001	.009	3	1
COAD	SIX6 →	+0.207	+5.542	<.001	<.001	3	1
COAD	TMEM167AP1 →	+0.368	+4.790	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 222 associations by consensus.

Exploration

KRTAP5-11 survival (RNA) · tumor vs normal (RNA) · all KRTAP5-11 data types