Q-omics provides the consensus-scored TMEM167AP1 profile across patient tissues and cancer cell-line models. TMEM167AP1 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in TGCT. Additionally, TMEM167AP1 RNA expression shows 4,019 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight TGCT, and LSCC as cancer lineages where TMEM167AP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes TMEM167AP1 survival associations across molecular data types. TMEM167AP1 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

TMEM167AP1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	8	TGCT (72)	view →

This table ranks reproducible TMEM167AP1 RNA expression–survival associations across cancer types. High TMEM167AP1 expression shows unfavorable associations in TGCT, BLCA, LGG, ESCA, THCA and COAD. The TGCT Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify TGCT as the clearest survival context for TMEM167AP1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	II,III,IV	0.501	0.996	<.001	72	view →
BLCA	DFS	Tertile	IV	0.216	0.487	.023	36	view →
LGG	DFS	Tertile	All	0.246	0.742	<.001	36	view →
ESCA	DFS	Tertile	All	0.370	0.557	.027	27	view →
THCA	OS	Tertile	All	0.783	0.941	.005	27	view →
COAD	DFS	Tertile	III,IV	0.264	0.654	.039	18	view →

Pink = unfavorable, green = favorable. all 8 lineages →

TMEM167AP1-TGCT (OS)

Kaplan–Meier survival curve for TMEM167AP1 RNA expression in TGCT: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with TMEM167AP1 in patient tissues and cancer cell lines. In patient samples, TMEM167AP1 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	4,019	LSCC (2020)	view →
Function (RNA)	2,686	STAD (1700)	view →