Across TCGA pan-cancer cohorts, KRTAP5-11 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of KRTAP5-11’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where KRTAP5-11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRTAP5-11 is over-expressed in tumor, although a few such as BRCA and LUSC show the opposite, repressed pattern.

KIRP, BRCA, and KIRC are the cancer types where KRTAP5-11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRTAP5-11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	All	+0.048	.018	3	view →
BRCA	All	III,IV	−0.018	.043	2	view →
KIRC	All	All	+0.016	.006	2	view →
THCA	Female	All	+0.035	.031	1	view →
LUSC	Male	II,III,IV	−0.015	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: KRTAP5-11 RNA expression & survival · all KRTAP5-11 data types