KLHL41

Across TCGA cell cohorts, KLHL41 mutation is significantly associated with the RNA expression of many other genes, with 419 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KLHL41-associated genes across cancer lineages are KRTAP9-1, DAZL, and OR8B12. Each is linked with KLHL41 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL41-to-partner and partner-to-KLHL41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP9-1 grouped by KLHL41-low versus KLHL41-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL41→partner) and Y-score (partner→KLHL41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRTAP9-1 →	+0.040	+5.247	<.001	.001	3	1
STOMACH	DAZL →	+0.027	+4.129	.005	.007	3	1
LUNG_NSCLC_LUAD	OR8B12 →	+0.070	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	SCN10A →	+0.004	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR8A1 →	+0.481	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR10D3 →	+0.090	+4.544	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 419 associations by consensus.

KRTAP9-1 by KLHL41 expression — BLOOD_Lymphoma

Explore this box plot interactively →