kinesin family member 20BGenealiases: CT90 · KRMP1 · MPHOSPH1 · MPP-1 · MPP1
Q-omics provides the consensus-scored KIF20B profile across patient tissues and cancer cell-line models. KIF20B expression is associated with patient survival in 28 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, KIF20B is differentially expressed in 16, with the highest sampling consensus in HNSC. Additionally, KIF20B RNA expression shows 20,887 significant protein co-abundance associations, with the highest sampling consensus in LUAD. Together, these results highlight ACC, HNSC, and LUAD as cancer lineages where KIF20B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for KIF20B — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes KIF20B survival associations across molecular data types. KIF20B RNA expression shows survival associations in the most cancer types (28), followed by mutation status (6) and mass-spec protein abundance (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible KIF20B RNA expression–survival associations across cancer types. High KIF20B expression shows unfavorable associations in ACC, LIHC, KIRP, MESO and KICH, but favorable associations in KIRC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for KIF20B RNA expression.
This table summarizes KIF20B tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 16, while mass-spec protein shows differences in 3. The strongest signals are observed in HNSC for RNA and HNSC for protein.
This table ranks reproducible tumor–normal expression differences for KIF20B. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. KIF20B shows higher tumor expression in HNSC, BLCA, KIRC, LUAD, STAD and KIRP. The HNSC box plot shows higher KIF20B RNA expression in tumor versus normal tissue (log2 FC = +1.209, t-test p < 0.001).
This table shows molecular features associated with KIF20B in patient tissues and cancer cell lines. In patient samples, KIF20B shows the broadest associations at the RNA and protein expression levels, with LUAD recurring as the lineage with the largest associated feature set. In cancer cell lines, KIF20B RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Leukemia, while CRISPR and shRNA rows add functional-dependency signals in LIVER and LARGE_INTESTINE.
