KIF20B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIF20B mutation is significantly associated with the RNA expression of many other genes, with 5,717 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF20B-associated genes across cancer lineages are RN7SL134P, SNRPGP7, and SLC25A4. Each is linked with KIF20B in more than 4 cancer types. Because this analysis shows association rather than direction, both KIF20B-to-partner and partner-to-KIF20B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by KIF20B-low versus KIF20B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF20B→partner) and Y-score (partner→KIF20B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRN7SL134P →+0.059+2.270.001.00735
CESCSNRPGP7 →+0.420+4.306<.001.00133
UCECSLC25A4 →+0.534+1.917<.001<.00133
UCECCCSAP →+0.398+1.696.001<.00133
UCECSFXN1 →+0.487+1.758<.001<.00133
UCECZFYVE19 →+0.319+1.914<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,717 associations by consensus.

RN7SL134P by KIF20B expression — SKCM

Box plot of RN7SL134P in KIF20B-low vs KIF20B-high samples in SKCM.

Explore this box plot interactively →

Exploration