KIF20B

Across TCGA pan-cancer cohorts, KIF20B RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated KIF20B data layer compared with 6 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher KIF20B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KIF20B expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

ACC, LIHC, and KIRP are the cancer types where KIF20B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.370	0.813	<.001	133	view →
LIHC	OS	Median	All	0.712	0.838	<.001	89	view →
KIRP	OS	Median	All	0.593	0.786	<.001	89	view →
MESO	OS	Median	All	0.405	0.672	<.001	81	view →
KICH	DFS	Tertile	II,III,IV	0.440	1.000	<.001	73	view →
KIRC	DFS	Median	All	0.749	0.486	<.001	72	view →
LUAD	OS	Tertile	All	0.249	0.467	<.001	58	view →
PAAD	OS	Quartile	All	0.220	0.587	<.001	51	view →
UCS	OS	Quartile	II,III,IV	0.639	0.209	.009	42	view →
UVM	DFS	Quartile	III,IV	0.177	0.832	<.001	41	view →
LGG	OS	Median	All	0.385	0.541	<.001	37	view →
BLCA	DFS	Quartile	II,III,IV	0.417	0.559	.009	33	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

KIF20B–ACC (OS)

Open the ACC breakdown →