KIF20B

Across TCGA patient cohorts, KIF20B mutation is significantly associated with the total protein of many other genes, with 58 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF20B-associated genes across cancer lineages are ATM, eEF2, and eIF4E. Each is linked with KIF20B in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF20B-to-partner and partner-to-KIF20B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by KIF20B-low versus KIF20B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF20B→partner) and Y-score (partner→KIF20B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.491	-2.446	<.001	<.001	3	3
UCEC	eEF2 →	+0.241	+2.169	.010	.002	3	2
UCEC	eIF4E →	+0.180	+1.584	.001	<.001	3	2
UCEC	ERK2 →	+0.163	+1.700	.001	.001	3	2
COAD	GAPDH →	+0.701	+3.178	.004	.010	2	3
UCEC	Heregulin →	-0.076	-1.266	.019	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

ATM by KIF20B expression — UCEC

Explore this box plot interactively →