KIF20B

Across TCGA cell cohorts, KIF20B mutation is significantly associated with the RNA expression of many other genes, with 853 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF20B-associated genes across cancer lineages are DEFB132, WNT8A, and MTMR4. Each is linked with KIF20B in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF20B-to-partner and partner-to-KIF20B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB132 grouped by KIF20B-low versus KIF20B-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF20B→partner) and Y-score (partner→KIF20B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DEFB132 →	+0.012	+5.369	<.001	.004	3	2
LUNG_NSCLC_LUAD	WNT8A →	+0.016	+2.481	.003	.005	3	2
LARGE_INTESTINE	MTMR4 →	+0.724	+3.584	<.001	<.001	3	2
LARGE_INTESTINE	BCAS2 →	+0.548	+2.265	<.001	.001	3	2
LARGE_INTESTINE	SETD7 →	+0.697	+2.949	<.001	<.001	3	2
LARGE_INTESTINE	RNF144A →	+0.800	+3.237	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 853 associations by consensus.

DEFB132 by KIF20B expression — SOFT_TISSUE

Explore this box plot interactively →