IGHV4OR15-8

Across TCGA patient cohorts, IGHV4OR15-8 RNA expression is significantly associated with the RNA expression of many other genes, with 7,266 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible IGHV4OR15-8-associated genes across cancer lineages are IGHV1OR15-2, IGHV3OR15-7, and IGHV3OR16-8. Each is linked with IGHV4OR15-8 in more than 31 cancer types. Because this analysis shows association rather than direction, both IGHV4OR15-8-to-partner and partner-to-IGHV4OR15-8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV4OR15-8 versus IGHV1OR15-2 in UVM, with a Pearson correlation of 0.96.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV4OR15-8→partner) and Y-score (partner→IGHV4OR15-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	IGHV1OR15-2 →	+3.437	+0.116	<.001	<.001	3	32
LUAD	IGHV3OR15-7 →	+2.061	+1.174	<.001	<.001	3	32
STAD	IGHV3OR16-8 →	+2.072	+1.449	<.001	<.001	3	32
STAD	IGHV3OR16-13 →	+2.464	+1.375	<.001	<.001	3	32
LUAD	IGKV1OR2-6 →	+2.322	+1.177	<.001	<.001	3	32
LUAD	IGKV1OR2-9 →	+1.106	+1.083	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,266 associations by consensus.

IGHV4OR15-8 vs IGHV1OR15-2 — UVM

Explore this scatter interactively →